Description
Overview: Chikungunya is a viral disease transmitted to humans by infected mosquitoes. The Chikungunya IgG & IgM Quantitative test measures the levels of two types of antibodies in the blood serum:
IgM Antibodies: These are the first antibodies produced by the body after infection, usually appearing 4-7 days after symptoms start. A high or rising level of IgM indicates a recent or current infection.
IgG Antibodies: These appear later, usually 10-14 days after the start of symptoms, and can persist for years. Their presence indicates a past infection and provides long-term immunity.
Clinical Significance: By measuring both IgG and IgM, doctors can determine the stage of the infection.
Positive IgM, Negative IgG: Suggests a very recent, acute infection.
Positive IgM, Positive IgG: Suggests a recent infection that is progressing.
Negative IgM, Positive IgG: Suggests a past infection and likely immunity.
Negative IgM, Negative IgG: Suggests no evidence of current or past infection, although it may be too early to detect antibodies if symptoms just began.
When is this test recommended?
To diagnose Chikungunya in patients presenting with characteristic symptoms like sudden high fever, severe joint pain (arthralgia), muscle pain, headache, and rash, especially those living in or returning from endemic regions.
To differentiate Chikungunya from other similar mosquito-borne diseases like Dengue or Zika virus.
Sample Requirements:
Specimen: Serum.
Container: Gold Top (SST) or Red Top Tube.
Preparation: No fasting is typically required.
